Italy versus Ireland was called off this weekend, Italy v England on March 14 has gone too - and the fate of the entire Six Nations championship remains up in the air as a result of the coronavirus outbreak.
But one match which definitely does go ahead at Twickenham on Saturday is England versus Wales - always THE big one for a Welsh nation.
And despite the uncertainty about the championship there is still a Grand Slam to play for, with France chasing that title against Scotland at Murrayfield the following afternoon.
But first, that Twickenham clash. Eddie Jones' side are 1/5 red-hot favourites to beat Wales with the pools.com , although there will doubtless be quite a few optimistic Welsh fans backing their side at 4/1 .
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