Timothy Ray Brown was known as the “Berlin patient,” the first person who was known to have been cured of HIV infection.Brown was working as a translator in Berlin in the 1990s when he was diagnosed with HIV.
He took protease inhibitors, allowing him to have a near normal life expectancy, but in 2006, he was also diagnosed with leukemia.
Dr. Gero Hütter pioneered an experimental treatment intended to cure both Brown’s leukemia and his HIV. The treatment used bone marrow and stem cell transplants, which are known to be effective against leukemia.
But Hütter sought to treat Brown’s HIV simultaneously by choosing a transplant donor with a rare gene mutation that offers HIV resistance.
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