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Scientists reverse ageing in human cells by 30 years in groundbreaking study
scientists have some good news there as well.Experts at the Babraham Institute, in Cambridge, have developed a method of reversing ageing in human skin cells – in some cases by up to 30 years.In a paper published in scientific journal eLife under the catchy title “Multi-omic rejuvenation of human cells by maturation phase transient reprogramming,” the researchers say they managed to restore the function of aged cells, making them behave like cells that are decades younger.The researchers wrote: “The magnitude of rejuvenation instigated by MTPR appears substantially greater than that achieved in previous transient reprogramming protocols.“In addition, MPTR fibroblasts produced youthful levels of collagen proteins, and showed partial functional rejuvenation of their migration speed.”Just perking up old skin cells would be a revolution in cosmetic medicine, but if the technique could be extended to different types of cells it could completely transform the way that we approach medicine.Professor Wolf Reik, a group leader in the Epigenetics research programme, said the work has "very exciting implications.He said: "Eventually we may be able to identify genes that rejuvenate without reprogramming, and specifically target those to reduce the effects of ageing."This approach holds promise for valuable discoveries that could open up an amazing therapeutic horizon."Dr Diljeet Gill, a postdoc working with Professor Reik added: “Our understanding of ageing on a molecular level has progressed over the last decade, giving rise to techniques that allow researchers to measure age-related biological changes in human cells.
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