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Grey’s Anatomy is closing out its 18th season with a bang that is bigger than usual as the season finale of the hit medical drama also marks its 400th episode, a milestone just a handful of TV series have reached.

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‘Grey’s Anatomy’ Boss Krista Vernoff Reflects on 400 Episodes: The Show’s Impact Is ‘Very Personal to Me’

Emily Longeretta In the ever-changing TV landscape, one thing remains key for lasting scripted shows: powerful storytelling. And it’s nearly impossible to discuss that without highlighting “Grey’s Anatomy” — the longest-running primetime medical drama in history.This month, the series created by Shonda Rhimes reaches a giant landmark. On May 26, the procedural will air its 400th episode, which also happens to be its Season 18 finale.Since its March 2005 debut, “Grey’s Anatomy” has been a watercooler show — and may be one of the last standing, especially in network TV.“Honestly, I can’t quite get my head around it,” says Krista Vernoff, who stepped in for Rhimes as showrunner in 2017.

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Ellen Pompeo on Whether or Not She Can See 'Grey's Anatomy' Continuing Without Her (Exclusive)

Ellen Pompeo at 's 400th episode red carpet earlier this month, where the actress, who stars as the show's namesake, Dr. Meredith Grey, shared whether or not she can see the long-running ABC drama going on without her.«Shonda and I, I think — we'll see, we'll see,» Pompeo shared.

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Second Stage Theater Releases Statement After ‘Deeply Unfortunate’ Leak Of Jesse Williams’ Full Frontal Scene

Jesse Williams has the backing of his theatre group.

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‘Grey’s Anatomy’ Star Jesse Williams Teases Jackson and April’s Return: The Show ‘Will Outlive All of Us’

Paging Dr. Jackson Avery. Jesse Williams will return to Grey’s Anatomy for a brief appearance in the 400th episode, and he teased that Japril fans will be very happy.

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Jesse Williams’ Full Frontal Nude Scene From Broadway Debut In ‘Take Me Out’ Leaks Online

Jesse Williams sparked an internet frenzy Monday after a nude video of him in the Broadway play Take Me Out emerged online.

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Ellen Pompeo Joins Her 'Grey's Anatomy' Co-Stars for 400th Episode Celebration in L.A.

Ellen Pompeo is celebrating a Grey’s Anatomy milestone!

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‘Grey’s Anatomy’ Celebrates Upcoming 400th Episode (TV News Roundup)

Wilson Chapman editorAfter almost 20 years of medical emergencies and juicy drama, “Grey’s Anatomy” is gearing up for its landmark 400th episode this May.Set to air on May 26, the 400th episode of the series will air as a two-part Season 18 finale. The episode’s plot remains unknown, but will feature the return appearance of cast members Jesse Williams and Sarah Drew, as the super couple Jackson and April (aka “Japril”).

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Jesse Williams And Sarah Drew Set ‘Grey’s Anatomy’ Return

Jackson and April are checking back into “Grey’s Anatomy”.

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Jesse Williams and Sarah Drew Set 'Grey's Anatomy' Return

Jesse Williams and Sarah Drew will be returning to the ABC medical drama for a special guest appearance on the season 18 finale airing May 26, ET can confirm. This marks the first time Williams and Drew will be back on in more than a year when they last appeared.While details regarding their return is being kept close to the vest, the duo's united front can only lead to speculation that Jackson and April's reappearance will serve as an update of sorts for viewers.Drew returned for an episode last season to help Williams wrap up his storyline in a satisfying way as he left the show after 12 seasons. Back in February, Williams was open to the idea of returning to “I’d consider it,” he said while promoting his Broadway debut in the revival of .

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Jesse Williams & Sarah Drew Returning to 'Grey's Anatomy' for Season 18 Finale

Jesse Williams and Sarah Drew are coming back to Grey’s Anatomy!

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Jesse Williams and Sarah Drew to Appear on ‘Grey’s Anatomy’ Season Finale

Kate Aurthur editorThe once-and-future “Grey’s Anatomy” super couple of Jackson and April — played by Jesse Williams and Sarah Drew — are set to appear on the finale of the medical drama’s 18th season on May 26, Variety has confirmed.Williams left “Grey’s Anatomy” last season, having played Jackson since the show’s sixth season. Drew, who’d departed the show in 2018, returned for a guest appearance in May 2021 to send Jackson off to his new life in Boston, where he was taking over his family’s foundation.

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Jesse Williams & Sarah Drew Returning to 'Grey's Anatomy' for Season 12 Finale

Jesse Williams and Sarah Drew are coming back to Grey’s Anatomy!

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Jesse Williams & Sarah Drew Returning To ‘Grey’s Anatomy’ As Jackson & April

EXCLUSIVE: Japril will be back on Grey’s Anatomy. Jesse Williams and Sarah Drew are set to reprise their roles as Jackson and April in the Season 18 finale of the ABC medical drama, which airs May 26.

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Why ‘Grey’s Anatomy’ Alum Sarah Drew Would ‘Never’ Rule Out a Return as April Kepner

Once a doctor, always a doctor. Sarah Drew made it clear that her season 17 appearance on Grey’s Anatomy as Dr. April Kepner might not have been her final bow.

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Sarah Drew Opens Up About 'Emotionally' Taxing Lifetime Movie, Possible 'Grey's Anatomy' Return (Exclusive)

Sarah Drew said her new Lifetime movie, took an emotional toll.Inspired by the memoir from Lizbeth Meredith, Drew plays Lizbeth, a mother, who after saying goodbye to her daughters for a visit with their father — her abusive ex-husband — discovers days later that he has kidnapped the children and taken them to Greece. For the next two years, fueled by memories of her own childhood kidnapping, Lizbeth travels to the White House and Greece, burning through every dime and favor to get her children back. One wrong move and her ex-husband will disappear with her girls.

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Lifetime Sets Premiere Dates For Two ‘Fallen Angels Murder Club’ Movies & ‘Stolen By Their Father’ Pic

Lifetime has set premiere dates for a pair of Fallen Angels Murder Club movies starring Toni Braxton and others and the Sarah Drew-led pic Stolen by Their Father. which Elizabeth Smart has joined as executive producer.

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Sarah Drew Wrote ‘Passionate Letter’ Over Her ‘Grey’s Anatomy’ Ending

Dr. April Kepner’s ending on “Grey’s Anatomy” could have looked a lot different if Sarah Drew had a say.

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Ellen Pompeo Says ‘Grey’s Anatomy’ Fans Believing The End Is Near Are ‘Not Far Off’

Ellen Pompeo is getting candid about the future of “Grey’s Anatomy”.

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The CW Cancels 'The Republic of Sarah' After One Season

The CW has canceled the freshman series The Republic of Sarah after just one season.

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Candidate Crush: Greys Anatomy's Jesse Williams' Instagram is a treasure trove of unseen & memorable pics

Grey's Anatomy stars Jesse Williams and Sarah Drew sent their fans into a frenzy when they reunited on the show. Later, in an Instagram Live session the two stars also discussed the fate of April Kepner and Jackson Avery and if there ever could be a possibility of a spin-off series.

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