OK, so the basic plot of Stargirl is the same in both. It's about what happens when a boy named Leo meets a former homeschooler named Susan Caraway who calls herself Stargirl. (As Saoirse Ronan said in Ladybird, Stargirl is her given name.
It was given to her... by her.) Ukelele in hand, she's unnaturally kind and eccentric and takes the school by storm until everyone starts to get annoyed with the stubborn way she defies fitting in.
There are some small cuts to characters from the book, like Leo's friend Kevin and Stargirl's ally Dori Dilson, and I don't personally think that the school is as mean to Stargirl in the movie as they are in the book (which is probably a good thing).
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