Females sleep less, wake up more often and get less restorative sleep than males, according to a new study. The findings, published in the journal Scientific Reports, shed new light on what causes sleep differences in men and women and could have broad implications for biomedical research, which for decades has focused on males. “In humans, men and women exhibit distinct sleep patterns, often attributed to lifestyle factors and caregiving roles,” said senior author Rachel Rowe, assistant professor of integrative physiology at University of Colorado Boulder “Our results suggest that biological factors may play a more substantial role in driving these sleep differences than previously recognised.” Sleep research has exploded in recent years, with thousands of animal studies exploring how insufficient sleep impacts risk of diseases like diabetes, obesity, Alzheimer’s and immune disorders—and how such diseases impact sleep.
Meanwhile, mice have often been the first to be tested to see whether new drugs, including medications for sleep, work and what the side effects are. READ MORE: Pharmacist recommends home made remedy costing pennies to shorten colds by as much as two days But many of those results may have been skewed due to a lack of female representation, the study suggests. “Essentially, we found that the most commonly used mouse strain in biomedical research has sex-specific sleep behaviour and that a failure to properly account for these sex differences can easily lead to flawed interpretations of data,” said first author Grant Mannino, who graduated with degrees in psychology and neuroscience.
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