Manchester United were poor for large portions of the game at the Red Bull Arena. RB Leipzig got off to a dream start as they found themselves 2-0 up after just 13 minutes of the game.
United had a mountain to climb in the second half, and things were made even worse when they went 3-0 down with 20 minutes to play.
Despite attempting a late comeback, they were unable to get the point they needed to progress to the knockout stages and were beaten 3-2.
The group has been a rollercoaster for United, having smashed Leipzig 5-0 in the first meeting between the two and beating Paris Saint-Germain 2-1 in France.
Read more on mirror.co.uk