Trains from Manchester Piccadilly to London Euston could be cancelled if a new strike by Avanti West Coast employees takes place next month.
A total of 300 members of the rail union TSSA are being balloted in a a dispute over pay, conditions and job security. Voting papers are being issued June 15 and if backed by members, a strike could take place as early as July 13.
The move comes after the details of the biggest outbreak of strike action in the rail industry in a generation were revealed earlier this week.
Avanti operates passenger train services and stations including from London Euston to Birmingham, Crewe, Liverpool, Manchester and Glasgow.
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