After back to back defeats to kick off their Group A campaign, Rangers need a victory against Brondby at Ibrox to keep qualification hopes alive.
The Danish champions have the advantage in the section over the Ibrox side with one point after a draw against Sparta Prague.
And that makes it - by Steven Gerrard's own admission - a must-win encounter if they are to have any chance of reaching the knockout stage for a third successive season.
The Light Blues will be without Glen Kamara who is suspended after his red card in the defeat to Sparta Prague in the Czech Republic which game after a home loss to French cracks Lyon.
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