She was confirmed to have died on Thursday at an assisted living facility in Albany, Georgia. Her death was announced by the Mathews Funeral Home, who included her death in their list of obituaries.
Her co-star Karolyn Grimes, who played Zuzu Bailey as a child, took to Facebook to share her heartbreak.She wrote: "We have another angel!
Virginia Patton Moss.She was 97 years old.She is now with her beloved Cruse.She will be missed!" An account for the Jimmy Stewart Museum also paid their respects.
A spokesperson said: “We are saddened to hear of Virginia Patton Moss’ passing.“She played Ruth Dakin Bailey (Harry’s wife) in ‘It’s A Wonderful Life’.
Read more on express.co.uk