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Emergency services were called to the crash on Tyldesley Road just before 7pm tonight (Friday). A male was taken to hospital from the scene.
The extent of his injuries - or any details of his age - have not yet been confirmed. Reports on social media suggest a cyclist was involved in the crash.
The air ambulance is also believed to have landed at the scene. Tonight, Tyldesley Road remains cordoned off between High Street and Hamilton Street.
Read more on manchestereveningnews.co.uk