substance. Dennis Quaid, who starred in the 2025 Oscar-nominated film “The Substance” with Demi Moore and Margaret Qualley, is confident that Moore will win big at the Academy Awards on Sunday. “I knew it like my second day working on that movie.
I told Demi she’s going to win an Oscar for it,” Quaid, 70, told the Post in a recent interview promoting his commercial with Woody Harrelson and Matthew McConaughey for the “True To Texas” campaign. “The Substance” is a body horror film written and directed by Coralie Fargeat.
The plot follows Elisabeth Sparkle (Moore), an aging Hollywood starlet whose producer Harvey (Quaid) lets her go because she’s no longer young.
As she desperately takes a shady black market drug called “The Substance” designed to create a younger version of herself, events spiral out of control.
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