Holby City is coming to an end this week after 23 years and over the last couple of decades, the hospital based soap has helped give many household names a leg up in the acting industry.
While fans and former cast members have lamented the hospital drama, with some of the show's most memorable characters returning for one last hurrah, it's nearly time to say goodbye.
The show, which began as a spin off to Casualty in 1999, has had cameos from more than a few now very famous faces over the years.
OK! takes a look at some of the most memorable cameos, including those who have gone on to take Hollywood by storm... Get exclusive celebrity stories and fabulous photoshoots straight to your inbox with OK!'s daily newsletter Olivia Colman She may now be a proud Oscar winner for her role of Queen Anne in The Favourite, and has more recently wowed audiences playing Queen Elizabeth in The Crown, but Olivia Colman once had a much less regal role in Holby City.
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