Dostarlimab explained after drug's incredible success in bowel cancer study

Holly Willoughby was left red-faced after becoming confused during a cooking segment on This Morning.The presenter and co-host Phillip Schofield welcomed Jun Tanaka, 50, on today's show (June 22) for a cooking segment.While the chef was cooking his one-pot summer lamb, he started explaining to the Dancing On Ice presenter the steps to take to reduce the sauce in the dish.The American-born Japanese-British television chef said: "Take the lid off, and it helps reduce the sauce down and intensifies the flavour."Believing he meant taking it out of the oven completely, an intrigued Holly asked: "But how does it reduce the sauce, just because it steams away?""Yeah because if you take the lid off it reduces down slightly and starts to caramelise on the top and so thickens it up," the 50-year-old explained."How clever is that! I would never think to do that!" Holly exclaimed.What, reducing a sauce? a baffled Phil asked. Holly informed him: "No but leaving it off the hob to reduce on its own, because you would reduce it on the hob but he said you just put it on the side.

Arrow Strikes For UK & U.S. Rights To Horror Pic ‘The Leech’

Neighbours stars may be some of the most beloved soap stars – but that doesn't mean they don't push things when it comes to red carpet.It's embarrassing enough anytime someone has a wardrobe malfunction, but imagine if it happened because their outfit was so risqué it was almost inevitable.Whether it was on the red carpet, on set, or in private, celebrities are just as likely to suffer from an outfit mishap as the rest of us.READ MORE: Neighbours Jemma Donovan's hottest snaps - string bikini, thigh-high split and minidressDespite being clad in some of the finest designer gowns, these stars' expensive clobber didn't quite hold them in like they were supposed to, leaving them vulnerable to some epic wardrobe blunders.Some of these Neighbours stars handled their wardrobe malfunctions like pros, with others looking completely mortified and sharing their gaffes on social media.Here are some of the Aussie cast’s most daring outfits ever.Blonde beauty Sarah Ellen came dangerously close to an embarrassing wardrobe malfunction when she posed on the red carpet at an exclusive Tiffany & Co event back in 2018.The then 21-year-old bravely went braless in a revealing jumpsuit that showed off quite a bit of side-boob as she posed side on in the pinstripe all-in-one, which was belted at the waist to accentuate her tiny waist.The actress turned fashion blogger teamed the attire with a matching blazer and accessorised with delicate jewels.Bombshell actress April turned heads when she stepped out for the Glamour on the Grid event in Melbourne ahead of the Australian Formula 1 Grand Prix earlier this yearThe 33-year-old narrowly avoided a nipple slip in her halter neck gown by bridal-wear designer Alin Le' Kal as she posed on the red

Refresh for latest…: For the second time in eight months, Tom Cruise thrilled attendees at the CineEurope exhibition conference, appearing live on stage here in Barcelona this morning to cap off Paramount’s slate presentation. The room again positively thundered with applause as everyone leapt to their feet for an extended standing ovation in honor of the Top Gun: Maverick star.

Netflix fans have been left baffled by new Chris Hemsworth movie Escape from Spiderhead.The thriller, based on George Saunders’ dystopian short story Escape from Spiderhead, was added to the streaming service on Friday (18 June), follows two prisoners who bond as they come to terms with their pasts in a state-of-the-art slammer.READ MORE: Thor: Ragnarok – Chris Hemsworth says filming was a MarvelThe pair are locked up in a prison run by a visionary played by Chris, who experiments on his subjects using mind-altering drugs.The film is directed by Joseph Kosinski, who directed smash-hit move Top Gun: Maverick, and is written by Rhett Reese and Paul Wernick, who are responsible first two Deadpool films.The movie shot to the top of Netflix’s worldwide charts just one day after release, but some viewers took to social media to claim they only heard about the film on its day it came out.One said: “Just watched Spiderhead on Netflix, the way they did not promote this film when its their best cast and overall the directing was brilliant is very in character for Netflix." Another added: “I just heard about the movie Spiderhead two hours ago and that s*** was fire. How did Netflix not promote it?” A third added: “Question @netflix why do u not promote #Spiderhead but would promote your other stuff which shouldn’t be named? It’s directed by #josephkosinski for heaven’s sake.” A week before Spiderhead ’s release, director and producer Peter Atencio complained the movie had not been given enough coverage.He wrote: “In seven days a streaming service is releasing a $100m+ movie starring one of the biggest movie stars on earth and directed by a guy with a movie in theatres currently that is the biggest smash hit of the year.

Demi Rose might be one of the most famous faces on the social media these days, but she's quite the enigma.The 27-year-old model is a master in dazzling the internet with her racy bikini shoots from all around the globe - she's even posed nude on occasion.The OnlyFans queen has racked up nearly 20million followers on Instagram, an incredible feat for someone who hasn't even been modelling for 10 years.READ MORE: Demi Rose's robe slips open as she breaks silence on engagement rumoursDemi was born in Birmingham, but her lavish lifestyle has since taken her around the world to places like Europe, Ibiza, Africa, the United States, Dubai and beyond.But despite being an internet sensation, Demi hasn't revealed much about her personal life and rarely gives interviews.It's left many fans wanting to know more about Demi, so Daily Star has dug up some of her rare admissions.Demi said she always wanted to be a model, but never expected to be where she is now.She also admitted she used to be bullied by other kids at school and didn't have a lot of friends - during a chat with Radio 1's Newsbeat.The influencer said: "I never expected this when I was younger, but it's something that I've had to learn to live with."I always wanted to get into modelling and when I eventually got there I classed it as a blessing because I grew up being bullied and didn't have many friends at all."She told the Dirty Mother Pukka podcast: "Everyone just used to like to pick on me, put chewing gum in my hair, like, just to wind me up for their own entertainment."It was during her school years that Demi was diagnosed with chronic fatigue syndrome, which she described "like depression".Chronic fatigue is characterised by long bouts of extreme tiredness.The

Diego Maradona made himself public enemy number one with his antics.During England’s World Cup quarterfinal encounter against Argentina in 1986, the little attacker rose the tallest and knocked the ball past Peter Shilton with his hand. The goal was given and Argentina went on to win the game 2-0.

TOWIE star, 40, left her followers in awe of her enviable figure as she took to Instagram with the stunning slew of snaps. Posing on a bed, the reality star oozed glamour and confidence as she sported a sultry look for the camera.Chloe wore a skimpy white one piece that drew attention to her assets and clung to her taut tummy.READ MORE:Reality TV stars who appeared on other shows before fame - Rylan to Amanda HoldenWorking her best angles, Chloe added a pop of colour to her look with a pair of pink framed Celine sunglasses.She wore her trademark tresses in loose waves and sported a glam makeup look, which featured a plump brown lip.The mum-of-one accessorised with a duo of gold bracelets and some gold rings.Captioning the stunning array of snaps, Chloe penned: "WAITING FOR NOTHING BUT THE SUNSET."Chloe's comments were inundated with adoring messages from her loyal legion of fans who couldn't wait to gush over her sizzling display."Wow my girl.

This Morning star Phillip Schofield was left in a fluster after his attempt to position a face mask went seriously wrong. Just hours after hosting the ITV show alongside Holly Willoughby on Tuesday (June 21), the 60-year-old presenter settled into bed for a pamper session. However, it wasn't exactly relaxing for Phillip as he struggled to position a transparent mask on his face.

Stacey Solomon has wowed her followers after installing a clever trick for her swimming pool during a recent renovation of her garden.The former X Factor star gave her Pickle Cottage - which she shares with fiancé Joe Swash - a bit of a makeover at the start of the year, with the work on a swimming pool for the couple's house finally completed recently.After showing off the work with a snap of herself, Joe and two of their children earlier this month, Stacey has been keeping us posted on her social media channels.READ MORE: Stacey Solomon shares Father's Day celebrations as Joe Swash spends the day with son HarryThe mum-of-four has continued to keep her fans updated as her children enjoyed playing in the pool over recent weeks, and she's now installed a clever feature outside to ensure they can easily access towels and suncream. As OK! reports, Stacey revealed that while Joe was busy playing with their children, she would be spending her afternoon installing a towel rack, hooks and two suncream dispensers outside.She wrote: "Joe and the kids are playing in the pool so I'm going to make a little towel/suncream wall," alongside a starstruck emoji, with the singer then filming the process as she went along.Stacey then showed off the two black dispensers she would be fixing to the wall, before getting to work on her new project.She told her fans: "These bottles are thermo cool bottles designed to keep what's inside cool and I put them under the shrubs so they'll always be shade too.

Mumsnet to criticise the local resident for welcoming feathered friends to the area.And she was particularly peeved because a seagull pooed on her baby.READ MORE: Baffled shoppers spot big flaw with Dunelm chopping board that gives them 'trust issues'The post reads: "[My] neighbour [is] constantly throwing food out to birds and now one s*** on my baby. A bird, not a neighbour for the last part…“It’s seagulls mostly.

Instagram followers, is known for her body positive posts.And her latest was no different, as Bree emphasised the importance of showing the 'real' her.READ MORE: Woman posts pics taken secs apart to 'prove influencers shouldn't be body goals'The influencer shared two side-by-side pictures of herself dressed in the same brown gym wear.However, on the left-hand side, she had covered up and breathed in to give an immaculate view.This compared to the right-hand side where Bree relaxed her tummy as showed it off in all of its natural glory.She then shared a host of similar pictures in various other lycra ensembles to prove her point.Captioning the post, Bree told her fans that her body image as well as her health and fitness has evolved so much over the years.She told them: "Mine went a little bit like… 2014-2017: feeling sorry for myself, yo-yo dieting, punishing my body, loathing any form of exercise, never leaving the house."2018 priorities: drop dress sizes, get thin, lots of cardio, constantly putting myself down, obsessed with “fixing” my external appearance."2019-2020 priorities: lift weights, eat well, get stronger, push hard, strict routine, stay lean, only wear activewear that makes my muscles pop!!!"2021-2022 priorities: learn to be kinder to myself, lead a flexible & balanced lifestyle, heal my relationship with food, focus on my health & happiness, increase my rest days, move in ways I enjoy, wear activewear that makes me feel supported, comfy and cute, live in the moment, take myself on dates, accept lifestyle & body fluctuations, appreciate what my body does for me, respect myself, take care of my body & mind, be myself & be proud."Get all the biggest Lifestyle news straight to your inbox. Sign up for the free

Love Island star Amber Beckford’s family and friends have deactivated her Twitter account following cruel messages from trolls.On Tuesday’s episode (June 22), Amber, 24, was dumped from the villa alongside Ikenna Ekwonna, 23.Following her exit, Amber’s family took to social media where they explained their decision to deactivate her Twitter account, explaining they needed to protect her mental health.READ MORE:Love Island's Gemma Owen's mum wows in plunging white dress with husband MichaelAmber’s sister Haylie, friends Hannah and Taz, and the Beckford family have issued a statement on behalf of the islander. They wrote on social media: “Hey all, Amber’s time in the villa has come to an end.

OnlyFans model Elle Brooke has put out a "casting call" for men looking to date her and a fellow adult star. Taking to her Instagram Story yesterday (June 21), Elle asked men to prepare a two-minute application video for her and Emily Black to review. She wrote: "Come and date us both this Saturday!"READ MORE: Pornhub legend Mia Khalifa back in London after scorching tour through EuropeThe dates will be filmed, with the footage uploaded to Elle and Emily's shared YouTube channel EB2.

Coronation Street star who is known for playing Abi Webster stunned fans with a gorgeous swimsuit snap showing she is taking advantage of the rare English warm weather.Sally Carmen looked worlds away from the drama of the cobbles as she relaxed in a hot tub over the weekend.She took to Instagram with a selfie of herself, smiling for the camera while wearing red floral swimwear and a pair of dark shades before adding a straw hat to keep her safe from the scorching sun.READ MORE: Corrie's Sally Carman pays sweet tribute to co-star fiancé as she gives health updateShe captioned the picture: "A sunny Friday evening to myself? It’s got hot tub written all over it."The comments section was soon flooded with supportive comments from her friends and her fans.Georgia Taylor, who plays Toyah Habeeb in the ITV soap, said: " Absolute babe,"While Kelly Neelan star Millie Gibson wrote: " Hottie."Asha Alahan actress Tanisha Gorey also commented: "Wow!!!!!" with an added flame emoji.But in response to Tanisha, Sally joked: "I look like ‘Driving Miss Daisy’ but I’ll take it."Meanwhile, Simon Gregson, aka Steve McDonald, couldn't help but joke: " I’ve got that swimsuit. #matchymatchy."On Sunday, Sally returned to the social media platform to pay a lovely tribute to her co-star fiancé Joe Duttine, who fans best know for portraying Tim Metcalfe.She gushed about her husband-to-be and her dad on Father's Day.Posting a picture of Joe and her father in a pub, the 41-year-old wrote: "Happy Father’s Day to these two legends.

This Morning fans were in tears after Shirley Ballas spoke about her brother's suicide. Phillip Schofield and Holly Willoughby welcomed the former Strictly judge, 61, to the ITV studio in Wednesday morning's instalment (June 22) to raise awareness about male suicide.Phil explained that This Morning a partnering with the charity, Calm who have just launched their new campaign on London's South Bank in the hope of saving lives.READ MORE:This Morning fans 'switch off' as they fume at 'rubbish' crystal tips for Summer SolsticeThe London display features of pictures of men who have taken their own lives, with Shirley's brother being one of them.Speaking about her brother's suicide that happened 20 years ago, the former ballroom dancer described her brother as a "powerhouse" who "everybody loved."She added: "He was everything to me, we spoke everyday at four o'clock.

Kerry Katona has called on her Atomic Kitten bandmates to reconcile in her latest column with OK!.The 41-year-old admitted to drifting from Liz McClarnon and Natasha Hamilton who she was in the band with until deciding to leave in 2000 when she fell pregnant.In her column, Kerry revealed she's not spoken to the other girls in years as she spoke about Girls Aloud reuniting for Race For Life in memory of their late bandmate Sarah Harding.READ MORE: Kerry Katona, 41, strips down to skimpy lace lingerie as she announces OnlyFans returnSaying she was friends with Sarah, who passed away from breast cancer last year, Kerry said it's a "lovely idea" what the Girls Aloud members are doing.For one day only, Nadine Coyle, Nicola Roberts, Cheryl and Kimberley Walsh, will get back together to try and raise funds for crucial medical equipment that may diagnose cancer sooner.Speaking about the pop group reuniting in memory of Sarah, Kerry said: "I think it’s nice the girls are coming together and it’s for such a brilliant cause."Kerry continued: "I’m not as close to the Atomic Kitten girls as I once was, and it does make me wonder what would happen if, God forbid, anything happened to one of us."We’ve not spoken for years.

Amanda Owen has treated fans with a previously unknown revelation about her body, explaining she has a 'tramp stamp' tattoo.The author and former model reflected on her inking following the news that she and her husband Clive had decided to call it a day on their marriage.While fans thought they knew everything they could know about the businesswoman, she shared that her inking is not what you would expect Amanda revealed to The Sun: "I have a tattoo of a sheep – a tramp stamp! READ MORE:Our Yorkshire Farm's Amanda Owen defended by Jeremy Vine after social services warning"Once upon a time it was a very neat Swaledale but after nine children I’m a bit stretched so it might not look so much like a sheep anymore…"Opening up about her personal life, the Our Yorkshire Farm matriarch added: "I have a love of rave and dance music.

Kerry Katona would definitely be up for Page 3 if it was to make a return - because "why the hell not?!" she says.The Atomic Kitten star, 41, would be keen to get involved with the controversial newspaper which was axed in 2015.Despite branding herself a "prude", Kerry claimed she would love to do it after former glamour modal Sam Fox had called for it to make a comeback.Speaking to OK!, Kerry said: "Former glamour model Sam Fox has called for the return of Page 3, as she thinks it’s a positive influence for women. I totally agree with her."I believe I got where I am today because of Page 3.

Love Island gave viewers a glimpse of the newest bombshell to enter the villa.The Islanders have only just waved goodbye to contestants Amber and Ikenna, who were dumped from the villa in a brutal double elimination last night.But the teaser for tonight’s episode revealed that a new girl is joining the rest of the Love Island line-up already.Viewers got a glimpse of a blonde beauty with curly locks strutting into the villa before the boys spotted her lounging in the sun.The brand new bombshell is singer and songwriter Antigoni Buxton.With Dami single and Ekin-Su and Jay’s relationship looking rocky, Antigoni’s entry into the villa could really start to shake things up for the Islanders.Here’s everything you need to know about the stunning bombshell, including her career, dating history and famous family member.Antigoni Buxton is a singer from North London.The 26-year-old also has Cypriot roots and describes her music as a mix of “hip hop with UK beats and Greek/Middle Eastern elements”.Antigoni was signed to Island Records when she was just 20 but has since left to start her own label Sirena Records.The singer released her latest single Hit List last month.But she’s taken a break from her music to join the cast of Love Island for this year’s series.Antigoni is looking to have some fun during her time in the villa, saying: "I really just want to say ‘yes’ to things. Why not? It’ll be fun."I’m a Cypriot girl and I love being in the sun.

It's been a marathon year for Rangers playmaker Joe Aribo after a packed season for both club and country.