Scottish independence, the NHS, climate change and transport are all likely to come up throughout the 70-minute debate on BBC One Scotland and the BBC News Channel.
Nicola Sturgeon ( SNP ), Anas Sarwar (Labour), Douglas Ross (Scottish Conservatives), Willie Rennie (Lib Dems) and Patrick Harvie (Scottish Greens) will go head-to-head for the fourth and final time in the election campaign live on TV.
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